Sunday, October 11, 2026
Fasting insulin and skin glycation
The skin is the only organ you can audit with the naked eye.
But what says the most about you isn't seen in the mirror.
Part of that process has a name: glycation. The sugar circulating in your blood sticks to proteins like collagen and leaves residues that accumulate over years.
That accumulation can be estimated. There is a device that illuminates the forearm and calculates how many of those residues are in the skin.
In the Lifelines study, with more than 72,000 Dutch adults without diabetes or cardiovascular disease at the start, that value was measured and they were followed for a median of four years.
Those who started with more glycation residues in their skin developed more type 2 diabetes, more cardiovascular disease, and died more.
And the detail that interests me most: that relationship held true even when glucose and glycated hemoglobin were normal.
It is an association in an observational study, not a proof of cause. But it points to something uncomfortable.
A standard glucose test can come back perfect for years while damage from sugar accumulates silently in your tissues.
The study did not measure insulin or wrinkles. I cannot tell you that dull skin is a risk marker; no one has proven it that way.
What we do know: glucose alone tells an incomplete story.
Your face does not lie. But what matters arrives before you can see it.
Your 1% improvement for today.
In your next blood work, ask for fasting insulin along with glucose. It doesn't come from the study, it's a prudent suggestion: two values from the same tube that help detect insulin resistance sooner.
This is what I cover in the Gray Hair and Wrinkle Protocol: If glycation accumulates in your collagen years before glucose gives it away, in my Gray Hair and Wrinkle Protocol I explain how to stop it.
Remember that I now sell only ONE access to the Gray Hair and Wrinkle Protocol per day.
The price is set by a Dutch auction.
It goes down throughout the day.
→ See the current price of the Gray Hair and Wrinkle Protocol