Wednesday, November 4, 2026
Japan implants new neurons into a Parkinson's patient. Here is what you can do for yours today.
«While we postpone, life speeds by.»
– Seneca
We wait for the medicine of the future for the brain. And we neglect the one we already have.
In Japan, it is now possible to implant new neurons into the brain of a person with Parkinson's.
The treatment is called Amchepry. It consists of donor stem cells converted into dopamine-producing neurons, the same ones that Parkinson's gradually destroys.
Japan approved it conditionally in March and its public insurance covers it: about $350,000 per patient.
The Kyoto University trial treated seven patients. Of the six evaluated at two years, four moved better without medication, and none experienced serious adverse effects.
But there is a nuance that almost no one mentions: there was no comparison group that underwent sham surgery.
And in Parkinson's, that matters. In previous transplant trials, when compared that way, the benefit disappeared.
It is a real breakthrough. But it arrives when the disease has already destroyed a good portion of those neurons.
The useful question is another one: what can you do for yours today.
A French study of more than 95,000 women tracked their physical activity for nearly three decades. The most active had 25% less Parkinson's than the least active.
The interesting thing is that the difference already existed many years before the diagnosis.
In other words, it does not appear that it was the disease, still hidden, that made them move less.
It remains an association in women, not proof of causation. But it points in the same direction as almost everything we know about the brain: it stays healthy by moving.
The best neuron is not the one they implant for you. It is the one you do not lose.
I do not wait to have neurons implanted. I prefer to protect the ones I have with an exercise plan and habits that have evidence behind them.
Your 1% improvement today. Compound interest that accumulates.
Do 20 minutes of exercise today that makes you breathe hard, such as climbing hills, cycling, or intervals, and repeat it three times this week.
This is what I cover in the Longevity Workshop: how I set up the exercise that protects the brain and the rest of the habits with the most evidence for aging with the neurons you already have.
Remember that I now only sell ONE access to the Longevity Workshop per day.
The price is set by a Dutch auction.
It goes down throughout the day.
→ See the current price of the Longevity Workshop